Do you remember your roommates in college? What were they like? Have they changed since you last saw them in that bar a few years back?
What kinds of morning routines did you or one of your siblings have as a child? Describe why it was important then and now, or why it seems more important now, or vice-versa.
Describe a character's voice in a way that juxtaposes it with an animal in nature (no zoos) and develop why it is significant.
Find out about a child's second fishing trip. Then recreate it.
Think back to a time when you had to walk home from school at an early age. What do you remember as the most significant point of contact? The dog in the way? The front porch? The friend's house that you had to stop by to wake up and get moving?
Write a letter to your worst enemy. Then mail it to yourself and stash it away someplace and leave it unopened until you 'find' it years later.
Find out who the person is next to you at a stoplight. Then write a story based on what you learn.
Describe a scene of something that is destructive by nature, such as logging, mining or manufacturing, then write a story about someone who makes a living at it.
Take a short fable and rewrite it in no less than 3,000 words.
Take that fable and write a haiku.
Write about a judgement call from a military perspective, such as a recruiter's wife who is approached by a son who wants to join the service during wartime.
Describe the best feeling you've had from a drug. Then the worst.
Take an old e-mail you've printed out or stashed away in an online file somewhere and write what was going on behind the scenes at the time. (I have one where a friend of mine mocks a weatherman and named the anchorman Bob Enyerheddonmykock. I shit you not.)